Pranicura 5
Pranicura 5
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Pranicura® 5 – Advanced Relief for Anal Itching, Fissures & Hemorrhoids
Finally break the itch–scratch cycle—for good.
Pranicura® 5 is a clinically formulated, over-the-counter treatment designed to relieve persistent pruritus ani (anal itching), fissure pain and irritation, and hemorrhoid pain and discomfort—without steroids or numbing agents.
Unlike products that rely primarily on temporary numbing, Pranicura 5 uses a patented, four-active formula that addresses the full cycle of irritation:
- Provides fast, cooling relief – calms itching, burning, pain, and the urge to scratch
- Controls excess moisture – helps keep irritated skin drier and more comfortable
- Protects vulnerable skin – reduces irritation from friction and stool contact
- Supports lasting comfort – improves the local environment instead of temporarily masking symptoms
It’s designed for both active relief and daily prevention, so you can manage flare-ups and stay comfortable long-term.
How Does Pranicura Work?
Chronic anal itching, fissure pain, and hemorrhoid pain or discomfort may feel different, but they are often aggravated by overlapping factors: irritated skin, heightened nerve signaling, excess moisture, friction, and stool contact. Scratching can further weaken the skin barrier, while bowel movements and wiping can repeatedly aggravate fissures and hemorrhoids—keeping the area painful, itchy, and difficult to calm.
Pranicura’s four active ingredients work together to address both the symptoms you feel—itching, burning, pain, and discomfort—and the local conditions that can allow irritation to persist.
Provides relief from itching, burning, and pain
Menthol 1% provides cooling analgesic relief that helps calm pain, burning, and nerve-triggered itching. Calamine 12.5% soothes redness and irritation, relieves itching, and helps dry areas affected by excess moisture or discharge.
Restores moisture balance
Kaolin 12.5% absorbs perspiration, drainage, and excess moisture from the skin’s surface, helping reduce dampness and maceration. At the same time, Glycerin 25% draws moisture into dry or cracked skin.
This complementary action is important: kaolin controls excess moisture around the skin while glycerin helps keep the skin itself hydrated and protected.
Protects vulnerable skin
Glycerin helps create a protective surface against friction and stool-related irritation, while kaolin helps maintain a drier, calmer local environment. Together, they give irritated or compromised skin a better opportunity to recover.
Itching, burning, and pain are calmed → scratching and overall discomfort decrease → excess surface moisture is absorbed → vulnerable skin is hydrated and protected → the skin barrier has a better environment in which to recover.
Instead of temporarily addressing one symptom, Pranicura works on itch and pain signaling, moisture imbalance, friction, and skin-barrier damage together.
Why Is Pranicura Different?
Pranicura is not a conventional cream built around one primary ingredient or one temporary form of relief. It is a patented formula built around a precise combination of four active ingredients, each included at a purposeful strength to address a different part of the problem.
Four active ingredients at meaningful strengths
Pranicura contains:
Together, these active ingredients make up 51% of the formula—more than half of every application.
The percentage matters because these are not small supporting amounts added to an otherwise conventional cream. Each active is present at a meaningful strength and performs a specific role, allowing Pranicura to provide cooling relief from pain and burning, calm persistent itching, manage excess surface moisture, and protect vulnerable skin in one application.
This exact combination and concentration profile is unique to Pranicura—and patented.
Even the cream base was designed differently
The patented design extends beyond the active ingredients to the cream base itself.
Pranicura contains no petroleum jelly—an important difference for a warm, enclosed, and moisture-prone area.
Where petroleum jelly can fall short
Petroleum jelly forms a thick, waterproof seal that can trap perspiration, drainage, and trace stool moisture against already irritated skin. Because it does not absorb moisture, prolonged dampness can cause maceration—leaving skin soft, fragile, and more vulnerable to friction and further breakdown. These warm, moist conditions can also favor yeast and bacterial overgrowth.
Petroleum jelly can also soften and spread with body heat, movement, and friction. It may transfer to clothing or wipe away during cleaning, carrying active ingredients with it and leaving less medication in contact with the affected area.
Pranicura’s approach
Pranicura takes a different approach. Its kaolin-and-glycerin cream framework is designed to remain where applied while forming a lighter, permeable protective layer. Kaolin absorbs excess surface moisture, glycerin keeps vulnerable skin hydrated and protected, and the active ingredients maintain contact with the affected area.
Pranicura protects without sealing in dampness or sliding away from where relief is needed.
Why common alternatives fall short
Prescription and steroid treatments
Suppress itching and inflammation but do not address ongoing moisture, friction, or skin-barrier damage. Repeated or prolonged use can thin and weaken sensitive skin, making it more vulnerable to continued irritation and recurrence.
Over-the-counter products
Usually rely on numbing agents or basic protectants. They may provide short-term comfort, but they do little to restore a compromised skin barrier or resolve chronic irritation. When the temporary effect wears off, the symptoms often return.
Homeopathic and natural remedies
Natural does not automatically mean effective. These remedies often lack the targeted action and potency needed for persistent pain, itching, inflammation, and irritation—making meaningful, lasting relief unlikely.
These alternatives treat isolated symptoms. Pranicura was designed to address the full problem.
Pranicura is not another variation of a standard cream. It is a patented formula created from the ground up for the overlapping challenges of chronic anal itching, fissure pain, and hemorrhoid discomfort.
Our 180-Day Money-Back Guarantee
Relief shouldn’t feel like another gamble.
Many people discover Pranicura after spending considerable time and money on products that provided little to no relief. That is why every purchase is protected by a straightforward 180-day money-back guarantee.
Try Pranicura for up to 180 days. If you are not satisfied, contact us for a full refund—no return required.
- 180 days to try Pranicura
- Full refund if you’re not satisfied
- No need to return the product
You have time to use Pranicura as directed and decide for yourself—without the pressure or risk of another short trial period.
Order by phone 24/7:
Call 763-250-1709 or toll-free 1-877-747-3499
I usually do not leave reviews, but wanted to share to encourage others. I had a horrible hemorrhoid surgery in December, and honestly, wish I would of waited and found Pranicura beforehand. I ended up getting a fissure and dealing with itching these past few months. I randomly found the Friendly Proctologist videos and he recommended Pranicura. I started it about 2 months ago, and the itching went away immediately. I only used it 2x a day, occasionally 3x a day. Bleeding stopped. I just saw my surgeon and he said the fissure had healed! He didnt know about Pranicura and was fine with me using it for the itching, but said this cannot actually heal the fissure. I did not say anything, but I beg to differ with him. I still deal with gut flares due to IBS, so I use Pranicura still after every bowel and at bedtime. The jar will last me forever!
Amazing product! I've been using for about 5 weeks and not totally healed but well on the way. Everyone needs to know about this product!
After trying almost everything available, both prescription, and off the shelf, this product is the only one to give me relief form my fissure, that, ive been suffering from for several months! Even better than the last prescription which cost me $160.00 CDN. I am down to using once a day now, after several weeks of using the product! Needs time but really works, at least for me!
Thank you!
Amazing product! I started getting more constipated in the last 2 years and was suffering with anal fissures for the last year and a half. The nitroglycerin I was originally prescribed was not working anymore and the healing time was increasing every time the tear opened up. I was getting frustrated and despondent and wanted to give this a try before getting surgery. Pranicura helped to speed up the healing time significantly. Excellent instructions and although the product was strong (you can really feel it working) , it worked well and I highly recommend it.
Excellent product. I wish I could give it 20 stars. Living life like it should be.
Really thankful to have found this product. The first time I used it I thought my butt hole was on fire lol,but it settled down. within a minute. This stuff really works great. Calms my severe itching and burning very fast. Ive been using it for the last 3 years
I have been suffering with fissures for two months, trying prescriptions and over the counter products. Pranicura has given me so much relief and I finally feel healing taking place. It is well worth the cost. A little goes a long way. Thank You!!!
I had high hopes for this. Ive been using every known diaper rash ointment for over two years for my itching, irritated skin. So when I received this product and read the directions to use a barrier for a week if it caused a burning sensation, my hopes deflated. I gave this a good try, but it burned every time, and using a barrier cream didnt help for two years so I knew a week wouldn not improve my condition enough that Pranicura wouldnt burn on contact. I did try anyway. I also used it despite the irritation in hopes it eventually helped. It did not.
I was very skeptical. I have had a sore itchy butt for the last 14 years. 4 different doctors gave no explanation and the best they could offer was a prescription for cortisone. With Pranicura, I experienced improvement almost immediately and after 6 weeks I am able to use it once or twice a week as necessary. My nightmare is over. Stick exactly to their program and don not over apply. It doesnt take much. I just wish I had found this solution years ago.
After hitting rock bottom in December with my symptoms and no helpful Rx meds, I found pranicura and I followed the protocol for 90-days starting 1/1 and on 4/1 I am symptom free. This is the only product AND TREATMENT PLAN that worked. Read the instructions and follow them. Stop using a bidet. And pay attention to regular maintenance, even when symptom free, and in 90-days, I hope your life will be better too.
GOOD STUFF. HIGHLY RECOMMENDED. AAA ALL THE WAY!
I was skeptical at first I tried everything nothing would work still had burning sensation when I go to the bathroom I saw the good reviews on this pranicurs5 I decide to try it after 2 weeks of trying it I was amazed the burning sensation went away now I am able to go to the bathroom and not be in any pain this stuff really works well
Prior to pranicura I struggled for months with other named brands and feel I developed an allergy to an ingredient that made my hemorrhoids worse. Once I started pranicura the itching and swelling immediately reduced and after a few short weeks my hemorrhoids healed. By far the best product I have used!
It burns severely at first but if you put lidocaine over it and bendover in front of a fan it helps. Give it time for the burn to go away and then the menthol is soothing.
I am so so grateful that I found this product after extensive searches and use of 3 other products that did not help, and in fact I think one made it worse! I had an extremely painful fissure and it was chronic. I had extreme pain every time I went to the bathroom. I often cried, and at one stage I didnt go to the toilet for 5 days as I was too scared to, which of course further exacerbated the problem. I took as directed, having it on all day and night for about 8 weeks. I saw improvement after about 2-3 weeks, so much less pain! And then huge difference by 8 weeks. Unfortunately I went through something at that time and fell off my consistent use, so didn't make it to the full 12 weeks. I am back on it and have been for about 2 weeks now so will see if I can be fully healed, but I must say my pain is now a 2 compared to a 9 before! My main issue now are two small skin tags at top and bottom of ants, as the fissure/s was/were both at the top and bottom when it got really severe. I just wish I found this sooner instead of suffering for so long, with persistent severe pain for at least 6 months and pain for at least a year and a half or more before that. Doctors should prescribe this as I've read many reviews where surgery was not effective, which is why I didnt go for that as well as being so scared about experiencing more pain than I was already in! Thank you pranicura, which I refer to as Miracle cream!
Very happy with product, eases the irritation from fissures
I would give it 5 stars if I was able to stop using it. It is a good treatment but is definitely not a cure from my experience.
Use all the time to keep things in check. Flare ups happen mostly with constipation. Stuff made my life normal again. Better than anything in the store. Thank goodness for this wonderful product. Thank you Pranicura.
It really does work
My fistula is not 100 percent cured but so far Pranicura has helped reducing itch. I am going to continue using it for 12 weeks to see if it actually cures Fistula.
It has a nice aroma but in my case the little alcohol in the products makes it inch had to cleaned away because it was uncomfortable to leaved it on
First of all, I am not a person who likes to write reviews, but this time, I cannot stay silent. I was dying from those diseases, hemorrhoids and anal fissures. I had already used more than thirty five medications, none of them were effective. I ended up in the ER where I passed out in front of the entrance door, because the pain was unbearable. Doctors prescribed medication, nothing worked, until I went on google and found Pranicura. I am thanking God every day asking Him to bless the people who created that life saver cream. Where would I be today, if I didn’t find this precious product that saved my life? This is an amazing product, it works the minute you apply it, its magical. I will definitely recommend this product to everyone suffering hemorrhoids and anal fissures. I am not miserable anymore and I am living my life to the fullest.
Thank you so much!
Disclaimer:
Use only as directed. Pranicura is an over-the-counter topical anorectal product formulated to help relieve itching, irritation, burning, and discomfort associated with anorectal conditions. Individual results may vary.
For external use only. Avoid contact with eyes. Do not use on deep or puncture wounds or serious burns. Stop use and consult a healthcare professional if symptoms persist, worsen, or last more than 7 days, or if symptoms clear and recur within a few days.
Consult a healthcare professional before use if you have a medical condition or are using other medications.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Information provided on this website is for informational purposes only and is not intended as medical advice. As indicated on the Drug Facts label, the product is intended for temporary relief of symptoms.
For questions or assistance, contact help@pranicura.com.